Revista de Odontologia da UNESP
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Revista de Odontologia da UNESP
Original Article

Analysis of randomized clinical trials and the relationship between periodontal disease and Diabetes mellitus

Análise de ensaios clínicos randomizados e a relação entre doença periodontal e Diabetes mellitus

Freitas, Adriana Rodrigues de; Xavier, Ângela; Sales-Peres, Arsenio; Sales-Peres, Silvia Helena de Carvalho

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Abstract

The aim of this study was to analyze the effect of periodontal treatment on glycemic control in Diabetes Mellitus, through a critical review of randomized clinical trials. We performed a search of scientific literature through the PUBMED database using the keywords “Periodontal diseases and diabetes mellitus” in articles published from 1999 to 2009, including only the studies about clinical trial. Initially identified 31 studies, but after reading the 15 articles were excluded because it was not the type of study selected. Of the 16 remaining articles, only 10 complied with the criteria adopted for this study. Regarding the type of diabetes studied 03 articles dealt only with type I, 06 were related to type II and only 01 was retrieved both forms of the disease (type I and II). It was concluded that the maintenance of periodontal health can reduce the indicators for development and progression of diabetes as periodontal treatment associated with systemic or local antimicrobial therapy can influence the glycemic control of the Diabetes.

Keywords

Periodontal diseases, Diabetes mellitus, diabetes complications, clincal Trial

Resumo

O presente estudo teve por objetivo analisar a influência do tratamento periodontal no controle glicêmico do Diabetes Mellitus, por meio de uma revisão crítica de ensaios clínicos randomizados. Realizou-se uma pesquisa da literatura científica por meio da Base de Dados PUBMED utilizando-se os descritores “Periodontal Diseases and Diabetes Mellitus”, em artigos publicados de 1999 a 2009, incluindo-se apenas estudos do tipo ensaio clínico. Inicialmente, foram identificados 31 trabalhos; porém, após a leitura dos artigos, 15 deles foram excluídos, uma vez que não se tratava do tipo de estudo selecionado. Dos 16 artigos restantes, apenas dez adequaram-se aos critérios adotados para este estudo. Em relação ao tipo de Diabetes estudado, três artigos tratavam apenas do tipo I, seis relacionavam-se ao tipo II e apenas um artigo analisou ambas as formas da doença (tipos I e II). Conclui-se que a manutenção da saúde periodontal pode reduzir os indicadores de risco para o desenvolvimento e a progressão do diabetes, enquanto que o tratamento periodontal associado à terapia antimicrobiana sistêmica ou local pode influenciar no controle glicêmico da doença.

Palavras-chave

Doenças periodontais, Diabetes mellitus, complicações do diabetes, ensaio clínico

References



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