Estudo clínico-histopatológico de 38 odontomas
Clinical-histopathologic study of 38 odontomas
Alves, P.M.; Santos, P.P.A.; Cavalcanti, A.L.; Queiroz, L.M.G.; Souza, L.B.
Rev. odontol. UNESP, vol.37, n4, p.357-361, 2008
Resumo
Dentre os tumores odontogênicos, o odontoma é o mais freqüente, sendo classificado em dois tipos: odontoma composto e odontoma complexo. O objetivo deste trabalho foi determinar as características clínico-patológicas de odontomas. Realizou-se um estudo observacional e retrospectivo por meio da análise de 2.278 laudos histopatológicos do laboratório do Serviço de Anatomia Patológica da Disciplina de Patologia Oral da Universidade Federal do Rio Grande do Norte, no período de 2002 a 2007. As variáveis estudadas compreenderam: tipo de odontoma (composto e complexo), faixa etária, sexo, raça e localização anatômica dos tumores. Os dados foram organizados com o Software SPSS 13 e a associação significativa entre as variáveis foi verificada por meio do teste Qui-quadrado considerando o valor para rejeição da hipótese nula de p < 0,05. A freqüência de odontoma correspondeu a 1,7% do total (38 casos), dos quais 20 acometeram homens e 18 acometeram mulheres. A raça branca e a faixa etária de 21-40 anos foram as mais acometidas, 63% e 87%, respectivamente. A média de idade foi de 32 anos (± 16,2). Em relação ao tipo, 17 casos eram odontomas compostos e 21 se constituíam em odontomas complexos. Não foi observada diferença estatisticamente significante entre os sexos (p > 0,05), mas verificou-se maior predileção dos odontomas compostos pelo sexo feminino, enquanto que os odontomas complexos foram mais freqüentes no sexo masculino. Quanto à região anatômica acometida pela lesão, houve maior predileção pela mandíbula (69% para os odontomas compostos e 62% para os odontomas complexos). Conclui-se que os odontomas complexos foram mais freqüentes que os odontomas compostos, acometendo mais o sexo masculino e a região posterior de mandíbula, embora sem diferença estatisticamente significante.
Abstract
Odontoma is the most frequent of the odontogenic tumors and is classified in 2 types: composite odontoma and complex odontoma. The aim of this study was to determine the clinicalhistopathological characteristics of odontomas. This study was a retrospective and observational investigation performed by the analysis of 2.278 histopathological reports from the laboratory of the Service of Pathological Anatomy of the Discipline of Oral Pathology of the Federal University of Rio Grande do Norte, Brazil, between 2002 and 2007. The studied variables comprised: type of odontoma (composite and complex), age group, gender, race and anatomic location of the tumors. The collected data were organized using the SPSS software version 13.0, and the existence of significant association among the variables were assessed by the chi-square test, considering p < 0.05 as the value for rejecting the null hypothesis. The frequency of odontomas corresponded to 1.7% of the total of cases (38 cases), 20 in men and 18 in women. Caucasians and the 21-40-year-old age group were the most affected, with 63% and 87% of the cases, respectively. The mean age was 32 ± 16.2 years. Regarding the type, 17 cases were composite odontomas and 20 were complex odontomas. There was no statistically significant difference (p < 0.05) between the genders, but it was observed a greater predilection of composite odontomas for females, while complex odontomas were more frequent in males. The mandible was the anatomic site most commonly affected by the lesions (69% for the composite odontomas and 62% for the complex odontomas). It may be concluded that complex odontomas were more frequent than the composite odontomas, affecting preferably the male gender and the posterior region of the mandible, even though not presenting statistically significant differences.
Keywords
Odontoma, odontogenic tumors, neoplasms
References
1. Cuesta SA, Albiol JG, Aytés LB, Escoda CG. Revisión de 61 casos de odontoma. Presentación de un odontoma complejo erupcionado. Med Oral. 2003;8:366-73.
2. Henriksson CO, Kjellman O. Complex odontoma. Oral Surg Oral Med Oral Pathol. 1964;18:64-9.
3. Mehra P, Singh H. Complex composite odontoma associated with impacted tooth. N Y State Dent J. 2007;73(2):38-40.
4. Neville BW, Damm DD, Allen CM, Bouquot JE. Patologia oral & maxilofacial. 2a ed. Rio de Janeiro: Guanabara-Koogan; 2004.
5. Owens BM, Schuman NJ, Pliske TA, Culley WL. Compound composite odontoma associated with an impacted cuspid. J Clin Pediatr Dent. 1995;19:293-5.
6. Cildir SK, Sencift K, Olgac V, Sandalli N. Delayed eruption of a mandibular primary cuspid associated with compound odontoma. J Contemp Dent Pract. 2005;6:152-9.
7. Tomizawa M, Otsuka Y, Noda T. Clinical observations of odontomas in Japanese children: 39 cases including one recurrent case. Int J Paediatr Dent. 2005;15(1):37-43.
8. Regezi JA, Sciubba JJ. Patologia bucal: correlações clinicopatológicas. 3ª ed. Rio de Janeiro: Guanabara- Koogan; 2000.
9. Hisatomi M, Asaumi JI, Konouchi H, Honda Y, Wakasa T, Kishi K. A case of complex odontoma associated with an impacted lower deciduous second molar and analysis of the 107 odontomas. Oral Dis. 2002;8:100-5.
10. Barnes L, Eveson JW, Reichart P, Sidransky D. World Health Organization. Classification of tumours. Pathology and genetics of head and neck tumours. WHO/IARC Press: Lyon; 2005.
11. Cardoso LC, Miyahara GI, Magro Filho O, Garcia Junior IR, Soubhia AMP. Odontoma combinado associado a dentes não irrompidos: relato de casos clínicos. Rev Odontol Araçatuba. 2003;24(2):47-51.
12. Tanaka A, Okamoto M, Yoshizawa D, Ito S, Alva PG, Ide F, et al. Presence of ghost cells and the Wnt signaling pathway in odontomas. J Oral Pathol Med. 2007;36:400-4.
13. Ajike SO, Adekeye EO. Multiple odontomas in the facial bones. Int J Oral Maxillofac Surg. 2000;29:443-4.
14. Lukes SM, Wachter KM. Compound odontoma: a case study. J Dent Hyg. 2003;77(1):47-9.
15. Yeung KH, Cheung CT, Tsang MH. Compound odontoma associated with an unerupted and dilacerated maxillary primary central incisor in a young patient. Int J Paediatr Dent. 2003;13:208-12.
16. Santos JN, Pereira Pinto L, Figueredo CRLV, Souza LB. Odontogenic tumors: analysis of 127 cases. Pesqui Odontol Bras. 2001;15:308-13.
17. Philipsen HP, Reichart PA, Praetorius F. Mixed odontogenic tumours and odontomas. Considerations on interrelationship. Review of the literature and presentation of 134 new cases of odontomas. Oral Oncol. 1997;33(2):86- 99.
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