Salivary cortisol, job stress, and periodontal disease in nursing staff
Cortisol salivar, estresse ocupacional e doença periodontal em enfermagem
Alessandra Arthuso ALVES; Arthur Maciel ARAUJO; Rebeca Ferreira BADARÓ; Maiara Campos Linhares SAMPAIO; Julia Saraiva de Almeida BARBOSA; Umberto Demoner RAMOS; Elizabeth Pimentel ROSETTI
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References
1 Miller GE, Chen E, Zhou ES. If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychol Bull. 2007 Jan;133(1):25-45.
2 Varma SV, Varghese S, Nair SV. Prevalence of chronic periodontitis and chronic stress in the south indian population. Cureus. 2023 Jan;15(1):e33215.
3 Ella RE, Agharandu AE, Osuchukwu E, Samson-Akpan P. Occupational stress and job performance among nurses in a teaching hospital, in South – South, Nigeria. Int J Curr Res Rev. 2021 Jun;13(11):12-7.
4 Lin YH, Jen HJ, Lin YK, Seo JD, Chang WP. Cortisol awakening response and stress in female nurses on monthly shift rotations: a longitudinal study. BioMed Res Int. 2022 Sep;2022 (1):9506583.
5 Tikhonova S, Booij L, D’Souza V, Crosara KTB, Siqueira WL, Emami E. Investigating the association between stress, saliva and dental caries: a scoping review. BMC Oral Health. 2018 Mar;18(1):41.
6 Fukui M, Hinode D, Yokoyama M, Yoshioka M, Kataoka K, Ito HO. Levels of salivary stress markers in patients with anxiety about halitosis. Arch Oral Biol. 2010 Nov;55(11):842-7.
7 Vivarelli S, Italia S, Teodoro M, Pollicino M, Vitello C, De Vita A, et al. Salivary biomarkers analysis and neurobehavioral assessment in nurses working rotation shifts: a pilot study. Int J Environ Res Public Health. 2023 Apr;20(7):5376.
8 Obulareddy VT, Chava VK, Nagarakanti S. Association of stress, salivary cortisol, and chronic periodontitis: a clinico-biochemical study. Contemp Clin Dent. 2018 Sep;9(6 Suppl 2):S299-304.
9 Baumeister SE, Reckelkamm SL, Grabe HJ, Nauck M, Klinger-König J, Völzke H, et al. Cortisol and periodontitis: prospective observational and mendelian randomization studies. Front Endocrinol. 2023 Mar;14:1100985.
10 Refulio Z, Rocafuerte M, de la Rosa M, Mendoza G, Chambrone L. Association among stress, salivary cortisol levels, and chronic periodontitis. J Periodontal Implant Sci. 2013 Apr;43(2):96-100.
11 Garbellotto GI, Reis FJ, Feoli AMP, Piovesan CH, Gustavo ADS, Oliveira MDS, et al. Salivary cortisol and metabolic syndrome component’s association. Arq Bras Cir Dig. 2018 Jun;31(1):e1351.
12 Zhang H, Chen B, Pan C, Zhang A. To evaluate the serum cortisol, salivary cortisol, and serum interleukin-1 B level in patients of chronic periodontitis with smoking and stress and without smoking and stress. Medicine. 2021 Aug;100(31):e26757.
13 Eke PI, Zhang X, Lu H, Wei L, Thornton-Evans G, Greenlund KJ, et al. Predicting periodontitis at state and local levels in the United States. J Dent Res. 2016 May;95(5):515-22.
14 Papapanou PN, Sanz M, Buduneli N, Dietrich T, Feres M, Fine DH, et al. Periodontitis: consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018 Jun;89(Suppl 1):S173-82.
15 Chhabria K, Bonnen M, Asper J, Carnaby GD. Feasibility and value of salivary cortisol sampling to reflect distress in head and neck cancer patients undergoing chemoradiation: a proof-of-concept study. Int J Oncol Res. 2022;5(2):043.
16 Gholami N, Hosseini Sabzvari B, Razzaghi A, Salah S. Effect of stress, anxiety and depression on unstimulated salivary flow rate and xerostomia. J Dent Res Dent Clin Dent Prospect. 2017;11(4):247-52. PMid:29354252.
17 Matiello V, Coelho BLP, Sato HK, Constantino M, Clemente MO. Análise dos níveis de cortisol salivar em pacientes com esclerose múltipla. Revista Brasileira de Neurologia e Psiquiatria. 2020 Maio-Ago; 24(2):108-22.
18 Alves MGM, Chor D, Faerstein E, Lopes CS, Werneck GL. Versão resumida da “job stress scale”: adaptação para o português. Rev Saude Publica. 2004 Abr;38(2):164-71.
19 Urbanetto JS, Magalhães MC, Maciel VO, Sant’Anna VM, Gustavo AS, Poli-de-Figueiredo CE, et al. Estresse no trabalho segundo o Modelo Demanda-Controle e distúrbios psíquicos menores em trabalhadores de enfermagem. Rev Esc Enferm USP. 2013 Oct;47(5):1186-93.
20 Peruzzo DC, Benatti BB, Ambrosano GM, Nogueira-Filho GR, Sallum EA, Casati MZ, et al. A systematic review of stress and psychological factors as possible risk factors for periodontal disease. J Periodontol. 2007 Aug;78(8):1491-504.
21 Haririan H, Andrukhov O, Böttcher M, Pablik E, Wimmer G, Moritz A, et al. Salivary neuropeptides, stress, and periodontitis. J Periodontol. 2018 Jan;89(1):9-18.
22 Refulio Z, Rocafuerte M, de la Rosa M, Mendoza G, Chambrone L. Association among stress, salivary cortisol levels, and chronic periodontitis. J Periodontal Implant Sci. 2013 Apr;43(2):96-100.
23 Rosalin YE, Santos TMM, Araújo CSA, Campos MLG, Saraiva PP. Relação entre doença periodontal e indicadores de estresse e depressão. Rev Salusvita. 2019;38(1):53-72.
24 Rosania AE, Low KG, McCormick CM, Rosania DA. Stress, depression, cortisol, and periodontal disease. J Periodontol. 2009 Feb;80(2):260-6.
25 Zhang H, Chen B, Pan C, Zhang A. To evaluate the serum cortisol, salivary cortisol, and serum interleukin-1 B level in patients of chronic periodontitis with smoking and stress and without smoking and stress. Medicine. 2021 Aug;100(31):e26757.
Submitted date:
08/25/2025
Accepted date:
09/22/2025
