Revista de Odontologia da UNESP
https://revodontolunesp.com.br/article/doi/10.1590/1807-2577.04521
Revista de Odontologia da UNESP
Original Article

Evaluation of periodontal indices in young adults submitted to chlorhexidine 0.12% mouthwash: a randomized clinical trial

Avaliação dos índices periodontais em adultos jovens submetidos a enxaguatório bucal a 0,12% de clorexidina: um ensaio clínico randomizado

Nathale Cruz BATISTA; Camila Possal de PAULA; Isis Andréa Venturini Pola POIATE; Edgard POIATE JUNIOR; Elizangela Cruvinel ZUZA; Gabriela Alessandra da Cruz Galhardo CAMARGO

http://dx.doi.org/10.1590/1807-2577.04521 Rev. odontol. UNESP, vol.50, e20210045, 2021
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Abstract

Abstract: Introduction: Gingivitis is a gingival inflammation which can often be treated with oral hygiene such as brushing, flossing, and an antiseptic mouthwash.

Objective: The aim of this randomized clinical trial was to clinically evaluate the effectiveness of 0.12% chlorhexidine (CHX) solution as an anti-inflammatory agent and for reducing the presence of plaque and inflammation in young adults.

Material and method: Thirty patients with gingivitis aged 18 to 30 years with a probing depth ≤ 3 mm and a minimum of 20 teeth in the whole mouth were selected and evaluated at baseline and 30 days after treatment. Periodontal clinical parameters were verified: plaque index (PI), gingival index (GI), Simplified Oral Hygiene Index (OHI-S), Simplified Debris Index (DI-S), and Simplified Calculus Index (CI-S) Patients were then randomly allocated into two groups: CHX Group, received chlorhexidine 0.12% labeled as solution 1, and Placebo Group, received saline solution labeled as solution 2. Both groups were included in a hygiene program and received mouthwash.

Result: Statistically significant differences between CHX and Placebo groups were observed for the variables PI, GI, DI-S, CI-S, and OHI-S (p<0.05 - Paired T Test) after 30 days. The CHX group presented improved GI compared to Placebo at 30 days. Chlorhexidine 0.12% was efficient in the control of periodontium inflammation.

Conclusion: It can be concluded that chlorhexidine as a mouthwash is efficient in improving periodontal indices in young adults, but it is still controversial whether age can influence GI and OHI-S.

Keywords

Gingivitis, chlorhexidine, periodontics, periodontal index, clinical study

Resumo

Resumo: Introdução: A gengivite é uma inflamação gengival que geralmente pode ser tratada com higiene oral, como escovação, uso do fio dental e um anti-séptico bucal.

Objetivo: O objetivo deste ensaio clínico randomizado foi avaliar clinicamente a eficácia da solução de clorexidina 0,12% (CHX) como um agente antiinflamatório e na redução da presença de placa e inflamação em adultos jovens.

Material e método: Trinta pacientes com gengivite com idade entre 18 e 30 anos com profundidade de sondagem ≤ 3 mm com mínimo de 20 dentes em toda a boca foram selecionados e avaliados no início do estudo e 30 dias após o tratamento. Foram verificados os parâmetros clínicos periodontais: índice de placa (IP), índice gengival (GI), Índice de Higiene Oral Simplificado (IHO-S), Índice de Debris Simplificado (DI-S) e Índice de Cálculo Simplificado (IC-S). A seguir, os pacientes foram alocados aleatoriamente em dois grupos: Grupo CHX, recebeu clorexidina 0,12% previamente identificada como solução 1 e grupo placebo, recebeu solução salina identificada como solução 2. Ambos os grupos foram incluídos em programa de higiene e receberam enxaguatório bucal.

Resultado: Diferença estatisticamente significante entre os grupos CHX e Placebo foi observada para as variáveis ​​PI, GI, DI-S, CI-S e OHI-S (p <0,05 - Teste T Pareado) após 30 dias. O grupo CHX melhorou a resposta ao GI em comparação ao placebo em 30 dias. Clorexidina 0,12% foi eficiente no controle da inflamação do periodonto.

Conclusão: Pode-se concluir que a eficácia da clorexidina como enxaguatório bucal na melhora dos índices periodontais foi confirmada em adultos jovens, mas ainda é controverso que a idade pode influenciar o IG e IHO-S.
 

Palavras-chave

Gengivite, clorexidina, periodontia, índice periodontal, estudo clínico

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