FINE STRUCTURE OF THE MERKEL CELL AND ITS ASSOCIATED TERMINAL AXON lN THE HARD PALATE MUCOUS MEMBRANE
Ultraestrutura da célula de Merkel e axomo terminal associado na mucosa do palato duro de camundongo
Watanabe, I-S
Rev. odontol. UNESP, vol.8, nÚnico, p.9-17, 1979
Abstract
Electron microscopic observations of Merkel cells and their intra-epithelial nerve endings are studied in the palatine mucous membrane of the mouse. The Merkel cells may be identified by the following characteristics such as situation on the basal layer of the palatine mucous membrane, dense core granules which are located in the cytoplasmic side towards to the terminal axon and several finger-like cytoplasmic protrusions. ln the terminal axon numerous mitochondria and small clear vesicles are noted. Desmosome type junctions are evident between terminal axon and Merkel cells and adjacent epithelial cells.
Keywords
Merkel Cells, Nerve Endings, Sensory Innervation, Palatine Mucous Membrane.
Resumo
Com a utilização de microscópio eletrônico de transmissão foram observadas as células de Merkel e a terminação nervosa associada em mucosa de palato duro de camundongos. Estas células podem ser identificadas pelas seguintes características: 1) localização na camada basal do epitélio; 2) presença de grânulos específicos electrondensos os quais são comumente localizados no citoplasma junto a terminação nervosa; 3) protrusões citoplasmáticas em forma de dedo são estendidas no espaço intecelular contactando com as células adjacentes; 4) o axônio terminal associado apresenta mitochondrias, microtúbulos e pequenas vesículas claras; e 5) zonas de contato do tipo desmosomos são formadas entre o axônio terminal e a membrana citoplasmática da célula de Merkel e entre a célula de Merkel e as células epitelias adjacentes.
Palavras-chave
Merkel Cells, Nerve Endings, Sensory Innervation, Palatine Mucous Membrane.
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