Revista de Odontologia da UNESP
https://revodontolunesp.com.br/article/588018d37f8c9d0a098b4e38
Revista de Odontologia da UNESP
Original Article

Flexural strength of an acrylic resin after incorporation of an antimicrobial polymer

Resistência à flexão de uma resina acrílica após a incorporação de um polímero antimicrobiano

Oliveira Júnior, N.M.; Paleari, A.G.; Rodriguez, L.S.; Marin, Danny Omar Mendoza; Pero, A.C.; Compagnoni, M.A.

Downloads: 2
Views: 592

Abstract

Introduction: The incorporation of antimicrobial agents in acrylic resins can be an alternative to prevent denture stomatitis in partial or complete denture wearers. However, these agents can affect the mechanical properties of denture base acrylic resin. Objective: This study investigated the effect of incorporation of antimicrobial polymer 2-tert-butylaminoethyl methacrylate (PTBAEMA) on flexural strength of an acrylic resin. Material and method: Rectangular specimens were from a denture base acrylic resin (Lucitone 550) containing 0% (control), 1, 2.5, 5 and 10% of PTBAEMA. Data of flexural strength were evaluated by one way ANOVA, followed by Tukey test (a = 0.05). Result: It was observed that flexural strength significantly decreased (p < 0.05) after the addition of PTBAEMA: 0% (91.3 ± 13.7A), 1% (71.4 ± 7.7B), 2.5% (9.4 ± 1.5C); 5% (7 ± 1.7C) e 10% (7 ± 1.2C). Conclusion: Flexural strength was detrimentally affected after incorporation of PTBAEMA. Future studies are necessary to evaluate if the 1% concentration allows clinical application for the acrylic resin studied, since flexural strength obtained was within ISO recommendations.

Keywords

Antimicrobial agents, acrylic resins, denture bases, denture complete.

Resumo

Introdução: A incorporação de agentes antimicrobianos a resinas acrílicas pode ser uma alternativa para evitar a estomatite protética em usuários de próteses totais ou parciais removíveis. Entretanto, estes agentes podem afetar as propriedades mecânicas das resinas acrílicas para base protética. Objetivo: Esse estudo investigou o efeito da incorporação do polímero antimicrobiano 2-tert-butilaminoetil metacrilato (PTBAEMA) na resistência à flexão de uma resina acrílica. Material e método: Foram confeccionados espécimes de formato retangular a partir de uma resina acrílica para base protética (Lucitone 550) contendo 0% (controle), 1, 2,5, 5 e 10% de PTBAEMA. Os dados de resistência à flexão foram avaliados por meio de análise de variância a um fator seguida pelo teste de Tukey (a = 0,05). Resultado: Observou-se que a resistência à flexão diminuiu significantemente (p < 0,05) após a adição de PTBAEMA: 0% (91,3 ± 13,7A), 1% (71,4 ± 7,7B), 2,5% (9,4 ± 1,5C); 5% (7 ± 1,7C) e 10% (7 ± 1,2C). Conclusão: A resistência à flexão foi adversamente afetada após a incorporação do PTBAEMA. Futuros estudos são necessários para avaliar se a concentração de 1% permite uma possível aplicabilidade clínica para a resina acrílica estudada, visto que nesta concentração a resistência à flexão está dentro do limite estabelecido pela ISO (65 MPa).

Palavras-chave

Agentes antimicrobianos, resinas acrílicas, bases de dentadura, prótese total.

References



1. Hoad-Reddick G, Grant AA, Griffiths CS. Investigation into the cleanliness of dentures in an elderly population. J Prosthet Dent. 1990; 64: 48-52. http://dx.doi.org/10.1016/0022-3913(90)90152-3

2. Arendorf TM, Walker DM. Denture stomatitis: a review. J Oral Rehabil. 1987; 14: 217-27. PMid:3298586. http://dx.doi. org/10.1111/j.1365-2842.1987.tb00713.x

3. Dhir G, Berzins DW, Dhuru VB, Periathamby AR, Dentino A. Physical properties of denture base resins potentially resistant to Candida adhesion. J Prosthodont. 2007; 16: 465-72. PMid:17672838. PMCid:2267395. http://dx.doi.org/10.1111/j.1532-849X.2007.00219.x

4. Douglas WH, Walker DM. Nystatin in denture liners-an alternative treatment of denture stomatitis. Br Dent J. 1973; 135: 55-9.

5. Douglas WH, Clarke DA. Physical and mechanical properties of nystatin-containing denture liners. J Prosthet Dent. 1975; 34: 428-34.

6. Cunha TR, Regis RR, Bonatti MR, Souza RF. Influence of incorporation of fluoroalkyl methacrylates on roughness and flexural strength of a denture base acrylic resin. J Appl Oral Sci. 2009;17:103-7.

7. Paleari AG, Marra J, Pero AC, Rodriguez LS, Ruvolo-Filho A, Compagnoni MA. Effect of incorporation of 2-tert-butylaminoethyl methacrylate on flexural strength of a denture base acrylic resin. J Appl Oral Sci. 2011;19:195-9. PMid:21625732.

8. Chow CK, Matear DW, Lawrence HP. Efficacy of antifungal agents in tissue conditioners in treating candidiasis. Gerodontology. 1999; 16: 110‑8. PMid:10825850. http://dx.doi.org/10.1111/j.1741-2358.1999.00110.x

9. El- Charkawi H, el-Said EA, Safouh HM , el-Raghi N. Effect of addition antimicrobial agents to denture reliners. Egypt Dent J. 1994; 40: 785‑90. PMid:9588157.

10. Lefebvre CA, Wataha JC, Cibirka RM, Schuster GS, Parr GR. Effects of triclosan on the cytotoxicity and fungal growth on a soft denture liner. J Prosthet Dent. 2001; 85: 352-6. PMid:11319532. http://dx.doi.org/10.1067/mpr.2001.115249

11. Collier PJ, Ramsey A, Waigh RD, Douglas KT, Austin P, Gilbert P. Chemical reactivity of some isothiazolone biocides. J Appl Bacteriol. 1990; 69: 578-84. PMid:2292521.

12. Silver S, Phungf le T, Silver G. Silver as biocides in burn and wound dressings and bacterial resistance to silver compounds. J Ind Microbiol Biotechnol. 2006; 33: 627-34. PMid:7766065. http://dx.doi.org/10.1007/s10295-006-0139-7

13. Gelman MA, Weisblum B, Lynn DM, Gellman SH. Biocidal activity of polystyrenes that are cationic by virtue of protonation. Org Lett. 2004; 6: 557-60. PMid:14961622. http://dx.doi.org/10.1021/ol036341+

14. Thorsteinsson T, Masson M, Kristinsson KG, Hjalmarsdottir MA, Hilmarsson H, Loftsson T. Soft antimicrobial agents: synthesis and activity of labile environmentally friendly long chain quaternary ammonium compounds. J Med Chem. 2003; 46: 4173-81. PMid:12954069. http://dx.doi.org/10.1021/jm030829z

15. Lenoir S, Pagnoulle C, Galleni M, Compère P, Jérôme R, Detrembleur C. Polyolefin matrixes with permanent antibacterial activity: preparation, antibacterial activity, and action mode of the active species. Biomacromolecules. 2006; 8: 2291-6. PMid:16903673. http://dx.doi.org/10.1021/bm050850c

16. Ottersbach P, Kossmann B. Eine neue klasse von bioziden. GIT Labor Fachzeitschrift. 2002; 46: 452-6.

17. Seyfriedsberger G, Rametsteiner Ka, Kern W. Polyethylene compounds with antimicrobial surface properties. Eur Polym J. 2006; 42: 3383‑9. http://dx.doi.org/10.1016/j.eurpolymj.2006.07.026

18. Barbosa DB, Souza RF, Pero AC, Marra J, Compagnoni MA. Flexural strength of acrylic resins polymerized by different cycles. J Appl Oral Sci. 2007; 15: 424-8. PMid:19089173. http://dx.doi.org/10.1590/S1678-77572007000500010

19. Sosna F, Ottersbach P, Kossmann B. Antimicrobial additives. United States Patent US6790910. 2004.

20. International Organization for Standardization. Specification 1567: denture base polymers. 2nd ed. Geneva: ISO; 1998.

21. Pero AC, Marra J, Paleari AG, de Souza RF, Ruvolo-Filho A, Compagnoni MA. Reliability of a method for evaluating porosity in denture base resins. Gerodontology. 2011;28:127-33. PMid:20015223. http://dx.doi.org/10.1111/j.1741-2358.2009.00347.x

22. Casemiro LA, Martins CHG, Pires-de-Souza FCP, Panzeri H. Antimicrobial and mechanical porperties of acrylic resins with incorporated silver-zinc zeolite – part I. Gerodontology. 2008; 25: 187-94. PMid:18194331. http://dx.doi.org/10.1111/j.1741-2358.2007.00198.x

23. Shibata T, Hamada N, Kimoto K, Sawada T, Sawada T, Kumada H, et al. Antifungal effect of acrylic resin containing Apatite-coated TiO2 photocatalist. Dent Mater J. 2007; 26: 437-44. PMid:17694755. http://dx.doi.org/10.4012/dmj.26.437
588018d37f8c9d0a098b4e38 rou Articles
Links & Downloads

Rev. odontol. UNESP

Share this page
Page Sections