Revista de Odontologia da UNESP
https://revodontolunesp.com.br/article/5880180d7f8c9d0a098b4a45
Revista de Odontologia da UNESP
Original Article

Avaliação clínica e microbiológica do uso de um creme dental contendo clorexidina a 1%

Clinical and microbiological evaluation of the use of a toothpaste containing chlorhexidine 1%

Meyer, A.C.A.; Tera, T.M.; Ito, C.Y.K.; Kerbauy, W.D.; Jardini, M.A.N.

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Resumo

O objetivo deste estudo foi avaliar a eficácia clínica e microbiológica de um creme dental com clorexidina a 1%, usado por um período de quatorze dias na redução do Índice de Placa, Índice Gengival e do Índice de Manchamento das superfícies dentais, bem como o impacto sobre os microrganismos salivares. Neste estudo duplo cego, os voluntários foram divididos em dois grupos, cada um com 15 participantes, sendo: 1) Teste - que fizeram uso de um creme dental com clorexidina a 1% e 2) Controle - que fizeram uso de um creme dental com semelhante formulação, porém sem a clorexidina a 1%. Um único examinador realizou a coleta da saliva e a avaliação dos índices ocorreu nos dias 0, 7 e 14. As amostras de saliva de cada paciente foram diluídas, semeadas e incubadas. Realizou-se a contagem das unidades formadoras de colônia por mililitro (UFC.mL–1) de saliva, a análise da porcentagem de redução dos microrganismos salivares e a comparação da contagem entre os dias 7 e 0, 14 e 0, e 14 e 7. Os dados foram avaliados estatisticamente pelo teste de ANOVA (p < 0,05). Neste estudo de curta duração não se observaram diferenças estatisticamente significativas entre os dois grupos (Teste e Controle) quanto aos Índices de Placa, Gengival e Manchamento. Entretanto, observou-se redução expressiva dos microrganismos salivares entre os dias 14 e 0 (p < 0,05). Comparando-se entre si os grupos 1) Teste e 2) Controle, observou-se diferença significativa entre os dias 7 e 14 (p < 0,05), sendo essa diferença maior no dia 14 (p = 0,0006).

Palavras-chave

Clorexidina, creme dental, índice de placa

Abstract

The aim of the present study was the evaluation of the clinical and microbiological efficacy on the reduction of salivary microorganisms and the impact on Plaque Index, Bleeding Index and Staining Tooth Index by using a 1% chlorhexidine toothpaste. This 14 days study applied a double-blind cross-over method over 2 groups with 15 volunteers each. The first one was a Test Group that used the 1% chlorhexidine toothpaste and the second one was a Control Group that used similar formulation toothpaste without the chlorhexidine. On the baseline, day 7 and day 14 one single examiner collected the saliva samples and measured the Plaque Index, Bleeding Index and Tooth Staining Index. After each collect, the saliva samples of each volunteer were diluted, spread and incubated. The total number of colony-forming units for mL (CFU.mL–1) was counted; the percentage of reduction of salivary microorganisms was analyzed and compared between the days 7 and 0, 14 and 0, 14 and 7. The data was statistically assessed according the ANOVA test (p < 0.05). This short-term study did not reveal a significant difference between the Test Group and the Control Group among the Plaque Index, Bleeding Index and Staining Tooth Index. However, there was a significant reduction of the salivary microorganisms between the days 14 and 0, (p < 0.05). Comparing the groups (Test and Control), there was a significant difference between the days 7 and 14 (p < 0.05), this difference was higher on the day 14 (p = 0.0006)

Keywords

Chlorhexidine, toothpaste, plaque index

References



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