Revista de Odontologia da UNESP
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Revista de Odontologia da UNESP
Review Article

Microbiologia das doenças periimplantares: revisão de literatura

Microbiology of peri-implant diseases: literature review

Melo, L.; Vitussi, T.R.C.; Andrade, J.A.; Walter, K.G.; Ferrari, D.S.; Shibli, J.A.

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Resumo

Vários estudos longitudinais têm reportado uma alta taxa de sucesso da utilização de implantes osseointegrados no tratamento reabilitador. Entretanto, outras investigações têm mostrado a perda de implantes osseointegrados por causa de infecções periimplantares ou trauma oclusal. A periimplantite é caracterizada pela presença de reações inflamatórias que afetam o tecido periimplantar sob função. Indivíduos portadores de periimplantes são colonizados por patógenos periodontais como Porphyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum e Treponema denticola, enquanto sítios periimplantares sadios são colonizados por cocos Gram-positivos.

Palavras-chave

Implantes dentários, doenças periodontais, microbiologia

Abstract

Longitudinal studies have reported a high success rate for rehabilitating treatment through the use of osseointegrated implants. However, other studies have reported osseointegrated implant failure due to peri-implant infections or occlusal overload. Peri-implantitis is characterized by the presence of inflammatory reactions that affect the peri-implant tissue under loading. Subjects with peri-implantitis harbor periodontal pathogens such as Porphyromonas gingivalis, Tannerella forsythia, Fusobacterium nucleatum and Treponema denticola while healthy peri-implant sites harbor cocos Gram-positives.

Keywords

Dental implants, periodontal diseases, microbiology

References

 


1. Socransky SS, Haffajee AD. Evidence of bacterial etiology: a historical perspective. Periodontol 2000. 1994;5:7‑25.

2. Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent Jr. RL. Microbial complexes in subgingival plaque. J Clin Periodontol. 1998;25:134-44.

3. Zambon JJ. Periodontal diseases: microbial factors. Ann Periodontol. 1996; 1(1):879-925.

4. Mombelli A, van Oosten Mac, Schürch E, Lang NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol. 1987;2:145-51.

5. Schou S, Holmstrup P, Keiding N, Fiehn NE. Microbiology of ligature-induced marginal inflammation around osseointegrated implants and ankylosed teeth in cynomolgus monkeys (Macaca fascicularis). Clin Oral Implants Res. 1996;7:190-200.

6. Shibli JA. Análise microbiológica da peri-implantite induzida por ligaduras em diferentes superfícies de implantes osseointegrados. Estudo em cães [dissertação de mestrado]. Araraquara: Faculdade de Odontologia UNESP; 2000.

7. Mombelli A, Feloutzis A, Brägger U, Lang NP. Treatment of peri-implantitis by local delivery of tretracycline: clinical, microbiological and radiological results. Clin Oral Implants Res. 2001;12:287-94.

8. Shibli JA. Etiologia, tratamento e progressão das peri-implantites [tese de doutorado]. Araraquara; Faculdade de Odontologia UNESP; 2003.

9. Shibli JA, Martins MC, Lotufo RFM, Marcantonio Jr. E. Microbiologic and radiographic analysis of ligature-induced peri-implantitis with different dental implant surfaces. Int J Oral Maxillofac Implants. 2003;18:383‑90

10. Shibli JA, Martins MC, Theodoro LH, Lotufo RFM, Garcia VG, Marcantonio Jr. E. Lethal photosensitization in microbiological treatment of peri-implantitis: a preliminary study in dogs. J Oral Science. 2003;45:17-23.

11. Shibli JA, Martins MC, Nociti Jr. FH, Garcia VG, Marcantonio Jr. E. Treatment of ligature-induced peri-implantitis by lethal photosensitization and guided bone regeneration: a preliminary histologic study in dogs. J Periodontol. 2003;74:338-45.

12. Mombelli A. Prevention and therapy of peri-implant infections. In: Lang NP, Karring T, Lindhe J, editors. Proceedings of the 3rd European Workshop on Periodontology. Berlin: Quintessenz Verlag; 1999. p. 281-303.

13. Mombelli A, Marxer M, Gaberthüel T, Grunder U, Lang NP. The microbiota of osseointegrated implants in patients with history of periodontal disease. J Clin Periodontol. 1995;22:124-30.

14. Listgarten M, Lai CH. Comparative microbiological characteristics of failing implants and perioontally diseased teeth. J Periodontol. 1999;70:431-7.

15. Nociti JR. FH, Toledo RC, Machado MAN, Stefani CM, Line SRP, Gonçalves RB. Clinical and microbiological evaluation of ligature-induced peri-implantitis and periodontitis in dogs. Clin Oral Implants Res. 2001;12:295‑300.

16. Apse P, Ellen RP, Overall CM, Zarb GA. Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: a comparison of sites in edentulous and partially edentulous patients. J Periodontal Res. 1989;24:96-105.

17. Augthun M, Conrads G. Microbial findings of peri-implant bone defects. Int J Oral Maxillofac Implants. 1997;12:106-12.

18. Lee KH, Maiden MFJ, Tanner ACR, Weber HP. Microbiota of successful osseointegrated dental implants. J Periodontol. 1999;70:131-8.

19. Hultin M. Factors affecting peri-implant tissue reactions [PhD Thesis]. Stockholm: Institute of Odontology, Karolinska Institute; 2001.

20. Plagnat D, Giannopoulou C, Carrel A, Bernard JP, Mombelli A, Belser UC. Elastase, α2-macroglobulin and alkaline phosphatase in crevicular fluid from implants with and without periimplantitis. Clin Oral Implants Res. 2002;13: 227-33.

21. Tillmanns HWS, Hermann JS, Tiffee JC, Burgess AV, Meffert RM. Evaluation of three different dental implants in ligature-induced peri-implantitis in the beagle dog. Part II. Histology and microbiology. Int J Oral Maxillofac Implants. 1998;13:59-68.

22. Hanisch O, Cortella CA, Boskovic MM, James RA, Slots J, Wikesjo UME. Experimental peri-implant tissue breakdown around hydroxyapatite-coated implants. J Periodontol. 1997;68:59-66.

23. Eke PI, Braswell LD, Fritz ME. Microbiota associated with experimental peri-implantitis and periodontitis in adult Macaca mulatta monkeys. J Periodontol. 1998;69:190-4.

24. Rosenberg ES, Torosoian JP, Slots J. Microbial differences in two clinically distinct types of failures of osseointegrated implants. Clin Oral Implants Res. 1991;2:135-44.

25. Leonhardt A, Adolfsson B, Lekholm U, Wikstrom M, Dahlen G. A longitudinal microbiological study on osseointegrated titanium implants in partially edentulous patients. Clin Oral Implants Res. 1993;4:113-20.

26. Papaioannou W, Quirynen M, van Steenberghe D. The influence of periodontitis on the subgingival flora around implants in partially edentulous patients. Clin Oral Implants Res. 1996;7:405-9.

27. Danser MM, van Winkelhoff AJ, de Graaf J, Loos BG, van der Velden U. Short-term effect of full-mouth extraction on periodontal pathogens colonizing the oral mucous membranes. J Clin Periodontol. 1994;21:484-9.

28. Danser MM, van Winkelhoff AJ, van der Velden U. Periodontal bacteria colonizing oral mucous membranes in edentulous patients wearing dental implants. J Periodontol. 1997;68:209-16.

29. Mombelli A, Lang NP. The diagnosis and treatment of peri-implantitis. Periodontol 2000. 1998;17:63-76.

30. Loesche W, Syed SA, Schmidt E, Morrison EC. Bacterial profiles of subgingival plaques in periodontitis. J Periodontol. 1985;56:447-56.

31. Beltrami M, Bickel M, Baehni PC. The effect of supragingival plaque control on the composition of the subgingival microflora in human periodontitis. J Clin Periodontol. 1987;14:161-4.

32. Omar AA, Newman HN, Bulman J, Osborn J. Darkground microscopy of subgingival plaque from the top to the bottom of the periodontal pocket. J Clin Periodontol. 1990;17:364-70.

33. Furuichi Y, Ramberg P, Krok L, Lindhe J. Short-term effects of triclosan on healing following subgingival scaling. J Clin Periodontol. 1997;24:777-82.

34. Dahan M, Timmerman MF, Van Winkelhoff AJ, Van der Velden U. The effect of periodontal treatment on the salivary bacterial load and early plaque formation. J Clin Periodontol. 2004;31:972-7.

35. Newman MG, Socransky SS. Predominant cultivable microbiota in periodontosis. J Periodontal Res. 1977;12:120-8.

36. Ali RW, Lie T, Skaug N. Early effects of periodontal therapy on the detection frequency of four putative periodontal pathogens in adults. J Periodontol. 1992; 63:540-7.

37. Lai CH, Listgarten MA, Shirakawa M, Slots J. Bacteroides forsythus in adult gingivitis and periodontitis. Oral Microbiol Immunol. 1987;2:152-7.

38. Kamyia I, Okuda K, Hara K. Flow-cytometric identification and detection of Porphyromons gingivalis by a LPS specific monoclonal antibody. J Periodontol. 1994;65:309-15.

39. Gräber HG, Wilharm J, Conrads G. Monoclonal antibodies against integrin subunits α6 and β1 inhibit migration of gingival epithelium in organ culture. J Periodontol. 1999;70:388-93.

40. Booth V, Lehner T. Characterization of thr Porphyromonas gingivalis antigen recognized by a monoclonal antibody which prevents colonization by the organism. J Periodontal Res. 1997;32:54-6.

41. Okada M, Hayashi F, Nagasaka N. PCR detection of 5 putative periodontal pathogens in dental plaque samples from children 2 to 12 years of age. J Clin Periodontol. 2001;28:576-82.

42. Socransky SS, Smith C, Martin L, Paster BJ, Dewhirst FE, Levin AE. “Checkerboard” DNA-DNA hybridization. Biotechniques. 1994;17:788-92.

43. Haffajee AD, Cugini MA, Dibart S, Smith C, Kent Jr RL, Socransky SS. Clinical and microbiological features of subjects with adult periodontitis who responded poorly to scaling and root planing. J Clin Periodontol. 1997;24:767-76.

44. Haffajee AD, Bogren A, Hasturk H, Feres M, Lopez NJ, Socransky SS. Subgingival microbiota of chronic periodontitis subjects from different geographic locations. J Clin Periodontol. 2004;31:996-1002.

45. Feres M, Haffajee AD, Gonçalves C, Allard K, Som S, Smith C, et al. Systemic doxycycline administration in the treatment of periodontal infections (I). Effect on the subgingival microbiota. J Clin Periodontol. 1999;26:775‑83.

46. Feres M, Haffajee AD, Allard K, Som S, Socransky SS. Change in subgingival microbial profiles in adult periodontitis subjects receiving either systemically-administered amoxicillin or metronidazole. J Clin Periodontol. 2001;28:597-609.

47. Ximenez-Fyvie LA, Haffajee AD, Socransky SS. Comparison of the microbiota of supra- and subgengival plaque in health and periodontitis. J Clin Periodontol. 2000;27:648-57.

48. Ximenez-Fyvie LA, Haffajee AD, Socransky SS. Microbial composition of supra- and subgingival plaque in subjects with adult periodontitis. J Clin Periodontol. 2000;27:722-32.

49. Slots J. The predominant cultivable microflora of advanced periodontitis. Scand J Dent Res. 1977;85:114‑21

50. Tanner ACR, Haffer C, Brathall GT, Visconti RA, Socransky SS. A study of the bacteria associated with advancing periodontitis in man. J Clin Periodontol. 1979;6:278-307.

51. Moore WEC. Microbiology of periodontal disease. J Periodontal Res. 1997;22: 335-41.

52. Moore WEC, Holdeman LV, Cato EP, Smibert RM, Burmeister JA, Ranney RR. Bacteriology of moderate (chronic) periodontitis in mature adult humans. Infect Immun. 1983;42:510-5.

53. Listgarten MA, Lindhe J, Helldén L. Effect of tetracycline and/or scaling on human periodontal disease. J Clin Periodontol. 1978;5:246-71.

54. Müller HP, Hartmann J, Flores-de-Jacoby L. Clinical alterations in relation to the morphological composition of the subgingival microflora following scaling and root planing. J Clin Periodontol. 1986;13:825-32.

55. Gmur R, Strub JR, Guggenheim B. Prevalence of Bacteroides forsythus and Bacteroides gingivalis on subgingival plaque of prosthodontically treated patients on short recall. J Periodontal Res. 1989;24:113-20.

56. Sbordone L, Ramaglia L, Gulletta E, Iacono V. Recolonization of the subgingival microflora after scaling and root planing in human periodontitis. J Periodontol. 1990;61:579-84.

57. Salcetti JM, Moriarty JD, Cooper LF, Smith FW, Collins JG, Socransky SS, et al. The clinical, microbial, and host response characteristics of the failing implant. Int J Oral Maxillofac Implants 1997;12:32-42.

58. Gatewood RR, Cobb CM, Killoy WJ. Microbial colonization on natural tooth structure compared with smooth and plasma-sprayed dental implant surfaces. Clin Oral Implants Res. 1993;4:53-64.

59. Berglundh T, Lindhe J, Marinello C, Ericsson I, Liljenberg B. Soft tissue reaction to de novo plaque formation on implants and teeth. An experimental study in the dog. Clin Oral Implants Res. 1992;3(1):1-8.

60. Palmisano D, Mayo JA, Block MS, Lancaster DM. Subgingival bacteria associated with hydroxylapatite-coated dental implants: morphotypes and trypsin-like enzyme activity. Int J Oral Maxillofac Implants 1991;6:313-8.

61. Talarico GM, Neiders ME, Comeau RL, Cohen RE. Phenotypic characterization of mononuclear cells from gingiva associated with periodontitis and peri-implantitis. J Oral Implantol. 1997;23(1/2):5-11.

62. Rams TE, Link CC. Microbiology of failing dental implants in humans: electron microscopic observations. J Oral Implantol. 1983;11:93-100.

63. Rams TE, Roberts TW, Tatum H, Keyes PH. The subgingival microbial flora associated with human dental implants. J Prosthetic Dent. 1984;51:529-34.

64. Holt R, Newman N. The clinical and microbial characterization of peri-implant environment. J Dental Res. 1986;65:257-62.

65. Ericsson I, Lekholm U. Evaluation of clinical function and marginal tissue reactions at tooth tissue-integrated reconstructions. In: van Steenberghe E, Albrektsson T, Bränemark PI, Henry PJ, Holt R, Liden G., editors. Tissue integration in oral and maxillo-facial reconstruction. Amsterdam: Excerpta Medica; 1986. p. 350. Current Clinical Practice, Series 29.

66. Mombelli A, Buser D, Lang NP. Colonization of osseointegrated titanium implants in edentulous patients. Early results. Oral Microbiol Immunol. 1988; 3;113‑20.

67. Sanz M, Newman MG, Nachnami S, Holt R, Stewart R, Flemmig T. Characterization of the subgingival microbial flora around endosteal sapphire dental implants in partially edentulous patients. Int J Oral Maxillofac Implants. 1990;5:247-53.

68. Becker W, Becker BE, Newman, MG, Nyman S. Clinical and microbiologic findings that may contribute to dental implant failure. Int J Oral Maxillofac Implants. 1990;5:31-3.

69. Mombelli A, Mericske-Stern R. Microbiological features of stable osseointegrated implants used as abutments for overdentures. Clin Oral Implants Res. 1990;1(1):1-7.

70. Ong ES, Newman HN, Wilson M, Bulman JS. The occurrence of periodontitis related microorganisms in relation to titanium implants. J Periodontol. 1992;63:200-5.

71. George K, Zafiropoulos GG, Murat Y, Hubertus S, Nisengard RJ. Clinical and microbiological status of osseointegrated implants. J Periodontol. 1994;65:766-70.

72. Papaioannou W, Quirynen M, Nys M, van Steenberghe D. The effect of periodontal parameters on the subgingival microbiota around implants. Clin Oral Implants Res. 1995;6:197-204.

73. Bollen CM, Papaioannou W, van Eldere J, Schepers E, Quirynen M, van Steenberghe D. The influence of abutment surface roughness on plaque accumulation and peri-implant mucositis. Clin Oral Implants Res. 1996;7:201-11.

74. Fardal O, Johannessen AC, Olsen I. Severe, rapidly progressing peri-implantitis. J Clin Periodontol. 1999;26:313-7.

75. Palmisano DA, Mayo JA, Block MS, Lancaster DM. Subgingival bacteria associated with hydroxylapatite-coated dental implants: morphotypes and trypsin-like enzyme activity. Int J Oral Maxillofac Implants. 1991;6:313-8.

76. Adonogianaki E, Mooney J, Wennström JL, Lekholm U, Kinane DF. Acute-phase proteins and immunoglobulin G against Porphyromonas gingivalis in peri-implant crevicular fluid: a comparison with gingival crevicular fluid. Clin Oral Implants Res. 1995;6(1):14-23.

77. Hart P, Watson CJ, Pollard M, Ogden AR. The microflora and pH of peri-implant fluid in peri-implantitis: a pilot study [abstract 306]. J Dent Res. 1996;75:1168

 

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