Foi analisada a resposta de auto-anticorpo natural no fluido gengival de indivíduos com o periodonto saudável e com periodontite. Pesquisaram-se duas diferentes especificidades: antitransferrina e antifibronectina. Os resultados mostraram que os níveis de auto-anticorpos para as duas proteínas estavam elevados na maioria dos indivíduos com doença periodontal quando comparados aos controles, principalmente com relação a fibronectina

The purpose of this study was to analyse the natural autoantibody response in healthy subjects and patients with periodontal disease. It was investigated two different specificities, antitransferrin and antifibronectin.The results shown high levels of autoantibody to either proteins in patients with periodontal disease when they were compared with controls. The great difference was observed to fibronectin