Reparação de feridas cutâneas submetidas ao tratamento com raio laser. Estudo histológico em ratos
Histalagic study of healing process in rats cutaneaus wounds treated by laser
Garcia, V.G.; Okamoto, T.; Kina, J.R.
Rev. odontol. UNESP, vol.25, n1, p.37-48, 1996
Resumo
O processo de reparação tecidual tem sido ao longo dos anos motivo de várias pesquisas. Desta forma, no presente trabalho foi estudado, por meio de análise histológica, o processo de reparação de feridas cutâneas provocadas por intermédio de um "PUNCH" de 8mm de diâmetro, na região dorsal de ratos, e submetidas ao tratamento com raio laser. Na análise comparativa dos eventos biológicos após os períodos de observação de 3, 7 e 14 dias, entre as feridas do Grupo Experimental (tratadas com raio laser) e as do Grupo Controle (que não receberam nenhum tratamento), podemos concluir que: as feridas do Grupo Experimental mostraram reparação mais evoluída que as do Grupo Controle: a) houve elevada taxa de migração epitelial; b) acentuada proliferaçâo fibroblástica e vascular; c) evolução mais rápida do quadro agudo para o crânico; os eventos biológicos foram mais evidentes nos períodos de 3 e 7 dias; não houve nenhum sinal de efeito indesejável da aplicação do raio laser sobre a reparação de feridas
Palavras-chave
Lasers, cicatrização de feridas, ratos
Abstract
The wound healing tissue has always been an excellent subject for researches. ln the present article the cutaneous wounds healing process was studied in the dorsal area of rats distributed into two groups, the Control Group (natural healing without treatment) and Experimental Group (treated with Laser). The wound was made by a punch with 8mm diameter. The wound healing process was evaluated on the third, seventh and fourteenth days after the surgery. A comparative analysis of these results between the two groups lead us the following conclusions: 1. the wound healing tissue was precociously observed in the Experimental Group; 2. there was an increased rate of epithelium migration in the Experimental Group; 3. there was an increased of fibroblastic and vascular proliferation in the Experimental Group; 4. the biologic changes were more evident on the third and seventh days after the surgery; 5. the laser healing treatment did not present any undesirable effect
Keywords
Lasers, wound healing, rats