Mineralização da mandíbula de ratos em função da administração de flúor
Mineralization of rat mandibles under fluoride administration
Santos-Pinto, L.A.M.; Rocca, R.A.; Mendes, A.J.D.
Rev. odontol. UNESP, vol.20, nÚnico, p.129-136, 1991
Resumo
A quantidade de cálcio, fósforo, magnésio e flúor foi avaliada na mandíbula de ratos com 30 e 60 dias de idade, que receberam, via bucal, doses diárias de 0,25 mg F, contidos em produto comercial tipo comprimido (Fluornatrium), a partir do nascimento. Os resultados obtidos evidenciaram que nos animais tratados o conteúdo de flúor foi maior aos 30 que aos 60 dias, ocorrendo o inverso com relação ao cálcio, não sendo observada nenhuma alteração nos teores de fósforo e magnésio.
Palavras-chave
Fluoreto de sódio, metabolismo e mineralização
Abstract
The dosage of calcium, phosphorus, magnesium and fluoride was analysed in rat mandibles that received 0,25 mg F contained into a commercial product, during 30 and 60 day period, beginning at birth. The results showed that the fluoride content was greater in 30 day old rats. The calcium concentration was greater in the 60 day old rats and no alteration was observed in the phosphorus and magnesium content.
Keywords
Sodium fluoride, metabolism and mineralization
References
1. BERGARA, C. Alterations dentaires et osseuses dans l' intoxication chronique par les fluorures. Compt. rendo Soe. Bio/., V. 97, p. 600-12, 1927.
2. BETHKE, R.M., KICK, C.H., EDGINGTON, R.H., WILDER, O.H. The effect of feeding sodium fluo ride and rock phosphate on bone development in swine. Proc. Am. Soe. Animal Production, V. 29, p. 33-9, 1929.
3. COLORIMETRIC DETERMINATION OF NON METALS. New York: Interscience Publishers, 1958, p. 203-27.
4. DEPARTAMENTO AUTÔNOMO DE ÁGUA E ESGOTO. Araraquara-Relatório de Atividades, 1986.
5. GEDALIA, 1., SINGER, L., VOGEL, 1.1., ARMSTONG, W.D. Fetal and neonatal fluo ride uptake by calcified tissues of rats./srael J. Med., V. 3, p. 726-30, 1967.
6. GORSUCH, T.T. The destruction %rganic marta. Oxford: Pergamion, 1970, p. 136-49.
7. HANDBOOK OF ATOMIC ABSORPTIONS ANALYSIS. Flórida: C.R.C. Press, 1985, p.29-34.
8. KAY, C.E., TOURANGEAU, P.C., GORDON, C.C. Industrial fluorosis in wild mule and whitetail deer from western Montana. Fluoride, V. 8, p. 1975.
9. KAY, C.E., TOURANGEAU, P.C., GORDON, C.C. Populational variation of fluo ride parameters in wild ungulates from the westem United States. Fluoride, V. 9, p. 73-90, 1976.
10. KRISHNARAO, G.V.G., TS'AO, K., DRAPER, H.H~·The effect of fluoride on some physical ans chemical characteristics of the bones of aging mice. J. Gerontol., v. 27, p. 183-7, 1972.
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