Adenocarcinoma polimorfo de baixo grau de malignidade do tipo papilífero. estudo morfológico e imuno-histoquímico
Polymorphous low-grade adenocarcinoma of the papillary type. A morphological and immunohistochemical study
Carvalho, Y.R.; Nogueira, T.O.; Souza, S.O.M.; Araújo, V.C.
Rev. odontol. UNESP, vol.19, nÚnico, p.165-171, 1990
Resumo
No presente trabalho foram estudados dois casos de adenocarcinoma polimorfo de baixo grau de malignidade do tipo papilífero, de glândulas salivares menores, através de microscopia de luz e imuno-histoquímica. Um dos casos exibiu predominância do padrão papilífero, enquanto o outro apresentou os seguintes padrões histológicos: papilífero, sólido, pseudocístico e tubular. Utilizando o método da peroxidase-antiperoxidase (PAP), o filamento intermediário vimentina, queratina e a proteína S100 foram observados nas células tumorais. A análise imunohistoqulmica revelou dois tipos de células neoplásicas: mioepitelial e luminal.
Palavras-chave
Neoplasias de glândulas salivares, adenocarcinoma, imuno-histoquímica
Abstract
Two cases or polymorphous low-grade adenocarcinoma or the papillary type, from minor salivary glands were studied by light microscopy and immunohistochemistry. One case exhibited a predominance or the papillary pattem, whereas the other presented the rollowing patterns or histological appearance: papillary, solid, pseudocystic mui tubular. Utilizing the peroxidase-antiperoxidase (PAP) method, the intermediate filament vimentin, keratin and 5100 protein were observed in tumor cells. The immunohistochemical analysis revealed two types of neoplastic cells: myoepithelial and luminal.
Keywords
Salivary gland neoplasms, adenocarcinoma, immunohistochemistry
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