Revista de Odontologia da UNESP
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Revista de Odontologia da UNESP
Original Article

Administração de parotin em ratas prenhes e seu efeito sobre o peso ponderal dos filhotes

Parotin administration in pregnant rats and its effect on the ponderal weight of the youngs

Matheus, G.

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Resumo

O peso corporal de 48 filhotes nascidos de ratas injetadas com Parotin apresentou-se aumentado em relação a 12 animais nascidos de ratas controle; sendo que aos 5 e 15 dias referido ganho de peso foi estatisticamente significativo. Igualmente os pesos absoluto e relativo da glândula submandibular apresentaram diferenças estatisticamente significativas aos 5 e 15 dias de vida.

Palavras-chave

Peso ponderal, Parotin, glândula submandibular

Abstract

The body weight of 48 newborn rats obtained after the injection of Parotin, increased in comparison to 12 animals borned from control rats. This increase of body weight was statistically significant at 5 and 15 days. Likely, both the absolute and the rela tive submandibular gland weights presented statistically significam differences on the 5th and the 15th day of life.

Keywords

Submandibular gland, Parotin, ponderal weight

References



1. BAKER, B. L. & ABRAMS, G. D. - Growth hormone (somatotropin) and the glands of the digestive system. ln: SMITH JR., R. W.; GAEBLER, H. O. & LONG, C. N. H. The hipophyseal growth hormone, nature and secretions. New York, McGraw Hill, 1954. p.107-22.

2. BIXLER, D.; WEBSTER R. C. & MUHLER, J. C. - The histochemistry of the adrenal cortex following removal of the major salivary glands. J. dento Res., 35:547-54, 1956.

3. CHATELUT, D. B. l.; DARNAULT, l.; DUBSC, Q. J. & DAVID, J. F. - Effects de I'ablation des glandes sous-maxillaires et de I'administration de "Parotine" sur la croissance du jeune ralo Endocrinologie, 164: 1680-4, 1970.

4. DEMETRIOU, N.; THEODOSSIOU, A.; BAZOPOULOU-KARKANIDOU, E. & SOTIRIOU, B. - Some histological observations on the pancreas, liver splun of salivariadenectomized albino rats. Odontoiatribe, 70:261-2, 1970.

5. FISHER, R. A. & YATES, F. - Tabelas estatísticas para pesquisa em biologia, medieina e agricultura. São Paulo. Polígono, Edil. Univ. São Paulo, 1971. p.15l.

6. GABE, M. - Contribution à I'histogénese des glandes salivaires chez la souris albinos. Z. Zellforsch, 45:74-95, 1956.

7. GODLOWSKI, Z.Z. - Endocrine function of submaxillary glands. Arch. atolar., 75:346-363, 1962.

8. GODLOWSKI, Z.Z. & CALANDRA, J. C. - Salivary glands as endocrine organs. J. appl. Physiol., 15:100-5, 1960.

9. GUIMARÃES, A.; TEIXEIRA, D.; VIZIOLI, M. R.; EL-GUINDY, M. M. & CURY, J. A. - Effects of salivary gland active principie (Parrotin) on glycalmic levei and hepatic glycogen content in alloxan-diabetic rats: Salivary gland active principie and diabetic rats. Arch. oral. Biol., 25: 11-3, 1980.

10. HALMOS, T. & SAMOGYI, B. - Investigations on the correlation between human saliva and carbohydrate metabolism. Nagy Belor. Arch., 15:220-5, 1962.

11. HIKI, Y.; BAN, T.; AKAZAKI, K.; TAKIZAWA, N. & MIYAZAKI, Y. - Experimental studies on the salivary gland. Trans. Jap. path. Soe., 20: 130-3, 1930.

12. INOUE, T. - Effects of alpha-parotin on tibral epyphyses with special reference to its made of actions. J. jap. Orthop. Ass., 37:851-62,1974.

13. ITO, Y. - Parotin: a salivary gland hormone. Ann. N. Y. Acad. Sei., 85:228-310, 1960.

14. ITO, Y. & MIZUTANI, A. - Studies on the salivary glands hormones. J. Pharm. Soe. Japan, 72:239-44, 1952.

15. ITO, Y.; MORIWAKI, C. & MORIYA, H. Studies on the oral administration of salivaparotin- A. II. Effects on the epiphyseal growth of tibia in rats. Endocr. Jap., 12:305-11, 1965.

16. ITO, Y. & TSURUFUJI, S. - Studies on the salivary gland hormone. XXIII. Effect of parotin on serum protein leveI. J. Pharm. Soe. Japan , 73:151-5,1953.

17. LIMA, J. E. O. - Influência da remoção das glândulas salivares maiores sobre o ganho de peso corporal e o desenvolvimento ósseo do rato. Bauru, Faculdade de Odontologia USP, 1978. (Tese-Doutoramento).

18. LISON, L. - Statistique apliquée a la biologie experimentale: la planification de l'experiénce et l'analyse des resultates. Paris, Gauthiers Villars, 1958. p.304.

19. LUCAS, D. R.; PEAKMAN, E. M. & SMITH, C. - The effect of insulin steroid and other hormones on the survival of the rat salivary gland in organ culture. Exp. Cell Res., 60:262-8, 1970.

20. MYANT, N. B. - Todine metabolism of salivary glands. Ann. N. Y. Acad. Sei., 85:208-14, 1960.

21. NARASIMHAN, M. J. & GANHA, V. G. - The regulatory influence of the submandibular salivary gland on growth. Ann. Endocr., 29:513-22, 1968.

22. OGATA, T. - Ueber die innere Skretion der mundspescheldrOsen. ln: Trans. 9th Congress Far. Eastern. Ass. Trop.Med., 1934. V.2. p.709-713. Apud OGATA, T. The internal secretion of salivary gland. Endocr. jap., 2:247-61, 1955..

23. OGATA, T. - The internal secretion of salivary gland. Endocr. jap., 2:247-61, 1955.

24. OGATA, A.; ITO, Y.; NOZAKI, Y.; OKADE, T. & ISHIT, Z. - Chemical and pathological studies on the isolation of :salivary hormone. Igaku-to-Seibutsugaku, 5:253-7, 1944.

25. OSÓRIO, J. A. & KRAEMER, A. - Effect of parotin on mice body weight. Rev. bras. Biol., 25:233-6, 1964.

26. PINHEIRO, C. E.; RAMALHO, A. C.; MACIEL, R. E. & MENEGATTO, G. - Balanço metabólico de lipídeos em ratos sialoadenectomizados. Arq. Cento Est;·.Cur. Odont. U. F. M.a., 15:83-8, 1978.

27. REDMAN, R.S. & SREEBNY~ L.M. - Proliferative behavior of differentiating cells the developing rat parotid gland. J. Cell Biol., 46:81-5, 1970.

28. REDMAN, R. S. & SREEBNY, L. M. - The prenatal phase of the morphosis of the rat parotid gland. Anat. Rec., 168: 127-138, 1970.

29. SHAW, J. H. & WOLLMAN, P. H. - The influence of sialoadenectomy in rats on food and water consuption. J. dento Res., 37:805-10, 1958.

30. SNEDECOR, G. W. - Statistical methods. 5. ed. Ames, Iowa States College Press., 1956. p.557.

31. TANAKA, S. & ITO, Y. - Studies on the salivary gland hormones. XXIX. Studies on the salivary gland hormones labeled with I l3l (1). Localization of radioactivity after administration of 1131 labeled parotin to rats. Endocr. jap., 5:55-64, 1958.

32. 'TAKIZAWA, N. - A pathological research on the internal secretion of salivary glands. Acta path. jap., 4: 129-66, 1954.

33. TUKEY, G. W. - The problem or multiple comparisons. Trans. N. Y. Acad. Sei., 16:88-97,1953.

34. YAMAGUSHI, T. - On the relation or the endocrine functions and the protein metabolism. Clin-Endocr., 2:1022-6,1954.

35. YUASA, K.; USHIKAWA, T.; YAMADA, N.; NINOMIYA, H. & TAKAOKA, Y. 1955 Effect of parotin on TCA-cycle. Naibumpi. Apud ITO, T.-Parotin: a salivary gland hormone. Am. N. Y. Acad. Sei., 85:228-310, 1960.
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