Revista de Odontologia da UNESP
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Revista de Odontologia da UNESP
Original Article

FLUORIDE INCORPORATION INTO DEVELOPING MOLAR TEETH OF RATS

Incorporação de flúor em molares em desenvolvimento em ratos.

Rosa Anita Rocca, Sérgio Miguel Zucas, Orlando Ayrton de Toledo

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Abstract

A quantitative analysis of fluoride was made in molar teeth of rats aged 10,20,30 and 60 days. The animals were daily injected subcutaneously, since birth to sacrifice, with 0,15 mg/NaF (0.067 mg/F) or 0.30 mg/NaF (0.134 mg/F). The comparative study of the data with those observed in molar teeth of rats without any treatment evidenced that: the adminiseered fluoride dosis did not affeet the molar teeth development or even the somatie growth of the animais as showcd by weighe evaluation; the molar teeth of rats exhibit gradual reduction of the eapacity for fluoride fixation durind mineralization process; and the percentual fixation of injected fluoride presented similar results for both tested dosis.

Keywords

Fluoride, tooth mineralization

Resumo

Foi efetuada a análise quantitativa do flúor presente nos molares de ratos com 10, 20, 30 e 60 dias de idade, que receberam, desde o nascimento, doses diárias de 0,15 mg/NaF ou 0,30 mg/NaF, injetadas subcutaneamente. O estudo comparativo dos dados obtidos, com aqueles observados nos molares de ratos da mesma idade, não tratados, evidenciou que: 1) as doses de flúor administradas não afetaram, de maneira consistente, o crescimento somático dos animais, nem dos molares; 2) os molares do rato perdem gradualmente sua capacidade para acumular flúor durante o processo de mineralização e 3) o percentual de flúor fixado mostrou comportamento similar para ambas as doses testadas.

Palavras-chave

Fluoride, tooth mineralization

References

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