Revista de Odontologia da UNESP
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Revista de Odontologia da UNESP
Original Article

Estudo do desenvolvimento de germes dentais de camundongos submetidos à ação transplacentária de aminoacetonitrila

Study of transplacentally acquired aminoacetonitrile on mice tooth germs development

Hetem, S.; Matheus, M.T.G.; Dekon, S.F.C.

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Resumo

Foi estudado o efeito do aminoacetonitrila, administrado durante o período de gestação, sobre o desenvolvimento dos germes dentais do camundongo. Os animais foram sacrificados a 1, 3, 8 e 10 dias após o nascimento. Verificou-se que o aminoacetonitrila retarda o desenvolvimento dos germes dentais, porém, não de maneira irreversível, uma vez que há uma recuperação da fase de desenvolvimento.

Palavras-chave

Odontogênese, aminoacetonitrila

Abstract

It was studied the effect of transplacentally acquired aminoacetonitrile during 3 days on mice tooth germs development. The offsprings were sacrificed at 1, 3, 8 and 10 days after birth. The results showed that aminoacetonitrile reversibly delays the tooth germs development, once that at 8 and 10 days after birth the morphologic aspects of tooth germs are quite similar.

Keywords

Odontogenesis, aminoacetonitrile

References



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